STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48989.1COGs: COG3920 Signal transduction histidine kinase; InterProIPR005467: IPR003594: IPR004358: IPR013656: IPR 011495; KEGG: kra:Krad_3796 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative two-component system sensor kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase; PAS fold. (494 aa)    
Predicted Functional Partners:
ADU48160.1
Response regulator receiver and ANTAR domain protein; COGs: COG3707 Response regulator with putative antiterminator output domain; InterPro IPR001789: IPR005561: IPR008327; KEGG: nca:Noca_3018 response regulator receiver; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; ANTAR domain.
 
   
 0.847
ADU47826.1
KEGG: aau:AAur_2578 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3039).
  
     0.649
ADU48990.1
COGs: COG2902 NAD-specific glutamate dehydrogenase; InterPro IPR007780; KEGG: bcv:Bcav_1575 NAD-glutamate dehydrogenase; PFAM: NAD-glutamate dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Bacterial NAD-glutamate dehydrogenase.
       0.646
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.621
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
     
 0.579
crgA
Protein of unknown function UPF0233; Involved in cell division; Belongs to the CrgA family.
  
     0.518
ADU50081.1
MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: pac:PPA2259 hypothetical protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Conserved membrane protein, MatE domain; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
  
   
 0.515
ADU46573.1
KEGG: kra:Krad_0008 hypothetical protein; SPTR: Putative integral membrane protein; PFAM: Transmembrane domain of unknown function (DUF3566).
  
     0.492
whiB-5
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.442
ADU48328.1
Regulatory protein MerR; InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein.
  
     0.432
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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