STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48993.1COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005931: IPR015590: IPR016160; KEGG: kse:Ksed_08740 delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; PFAM: Aldehyde Dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase 1; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1. (542 aa)    
Predicted Functional Partners:
ADU47186.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: ami:Amir_1081 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
 0.978
ADU47673.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: amd:AMED_2662 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Putative proline dehydrogenase; PFAM: Proline dehydrogenase.
 0.970
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.939
ADU50009.1
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR010164: IPR005829; KEGG: gob:Gobs_2808 ornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: RocD1; TIGRFAM: ornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.934
ADU49234.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362: IPR006095: IPR006097: IPR006096; KEGG: nfa:nfa45920 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Putative glutamate dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.916
ADU48543.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008147: IPR008146; KEGG: tbi:Tbis_1258 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
 
 0.908
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.907
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.907
ADU48158.1
Glutamate synthase (NADH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017896: IPR000759: IPR013027: IPR006005; KEGG: kfl:Kfla_3075 glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase, NADH/NADPH, small subunit 1; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit.
    
 0.907
ADU48539.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008147: IPR008146: IPR004809; KEGG: kra:Krad_3291 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
 
 0.906
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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