STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49008.1Protein of unknown function DUF1006; COGs: COG3214 conserved hypothetical protein; InterPro IPR009351; KEGG: kse:Ksed_08640 hypothetical protein; PFAM: protein of unknown function DUF1006; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1006). (402 aa)    
Predicted Functional Partners:
ADU49009.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sro:Sros_1417 response regulator receiver protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
       0.773
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
       0.667
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
       0.580
ADU49011.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: gob:Gobs_4282 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain.
       0.521
ADU49012.1
Lipoprotein LpqB, GerMN domain; InterPro IPR019606: IPR018910; KEGG: kse:Ksed_08610 lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB, GerMN domain; Lipoprotein LpqB, beta-propeller domain-like; SPTR: Lipoprotein LpqB family protein/sporulation and spore germination protein; PFAM: Lipoprotein LpqB beta-propeller domain; Sporulation and spore germination.
 
     0.491
ADU47085.1
Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551: IPR015358: IPR010211; KEGG: tcu:Tcur_2818 transcriptional regulator, MerR family; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: MerR family regulatory protein; MerR, DNA binding; TIGRFAM: redox-sensitive transcriptional activator SoxR.
  
     0.428
ADU48693.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  
  
 0.412
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.