Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49011.1COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: gob:Gobs_4282 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain. (282 aa)    
Predicted Functional Partners:
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.882
ADU48790.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kra:Krad_1409 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
 
 0.847
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.807
ADU48348.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099: IPR002912; KEGG: kra:Krad_3118 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; ACT domain.
   
    0.803
ADU49365.1
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680: IPR003764; KEGG: tfu:Tfu_2473 N-acetylglucosamine 6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
  
    0.800
ADU46868.1
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: gbr:Gbro_4728 integrase family protein; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: Putative transposase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family.
   
    0.769
xerC
Tyrosine recombinase XerC subunit; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
   
    0.769
ADU48418.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
    0.651
ADU48769.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
    0.651
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.648
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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