STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADU49020.1COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843; KEGG: kra:Krad_3841 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Putative phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomuta [...] (486 aa)    
Predicted Functional Partners:
ADU49018.1
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase; InterPro IPR019490: IPR006162; KEGG: kra:Krad_3839 putative transcriptional regulator, RpiR family; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; SPTR: Putative uncharacterized protein; PFAM: Bacterial phospho-glucose isomerase C-terminal region.
  
 
  0.981
ADU47724.1
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: nca:Noca_1407 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
 
 
 0.960
ADU47742.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005844: IPR005845: IPR005846: IPR005843: IPR 016066; KEGG: kse:Ksed_08160 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Putative phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutas [...]
     
0.933
ADU49431.1
COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: kse:Ksed_18490 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase.
 
 
 0.927
ADU49019.1
Protein of unknown function DUF343; InterPro IPR005651; KEGG: ske:Sked_09130 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: Putative uncharacterized protein; PFAM: Trm112p-like protein.
       0.820
ADU49017.1
Protein of unknown function DUF808; COGs: COG2354 conserved hypothetical protein; InterPro IPR008526; KEGG: cfl:Cfla_2445 protein of unknown function DUF808; PFAM: protein of unknown function DUF808; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF808).
       0.762
ADU48905.1
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: kra:Krad_1298 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Phosphorylase; TIGRFAM: alpha-glucan phosphorylase; manually curated; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
 
  
 0.733
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
   
 0.704
ADU49021.1
KEGG: sen:SACE_6461 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3499).
       0.693
ADU47418.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR002618: IPR005110: IPR001453: IPR005111: IPR 020817; KEGG: kfl:Kfla_5768 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase; MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-termi [...]
  
 0.623
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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