STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49030.1Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607; KEGG: tfu:Tfu_0551 putative lipoprotein; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative lipoprotein. (437 aa)    
Predicted Functional Partners:
ADU49031.1
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674; KEGG: tbi:Tbis_2919 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: HDIG domain protein; PFAM: HD domain.
     0.963
ADU47880.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR018486: IPR010822: IPR001932; KEGG: nca:Noca_3481 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Putative integral membrane protein; PFAM: Stage II sporulation protein E (SpoIIE).
 
    0.723
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.672
ADU49032.1
Hypothetical protein.
       0.628
ADU50107.1
KEGG: cfl:Cfla_3716 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.613
ADU47790.1
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: kse:Ksed_08480 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase; PFAM: Glycosyl transferase family 2.
  
    0.581
ADU50106.1
KEGG: ske:Sked_37910 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.569
ADU47303.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E (SpoIIE); MASE1.
  
    0.562
ADU48622.1
KEGG: ske:Sked_14030 hypothetical protein; SPTR: DNA primase.
  
     0.544
ADU47767.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003661: IPR003594: IPR005467; KEGG: cfl:Cfla_2388 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative two-component system sensor kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.512
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.