Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49033.1Anti-sigma factor; InterPro IPR014295; KEGG: ace:Acel_0539 anti-sigma factor; SPTR: Anti-sigma factor; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family. (96 aa)    
Predicted Functional Partners:
ADU49034.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014293: IPR014284: IPR007627: IPR013249; KEGG: art:Arth_2651 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02947 family.
  
 
 0.954
ADU47141.1
COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: kra:Krad_0528 hypothetical protein; PFAM: Protein of unknown function DUF2342; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: putative hydrolase; uncharacterized protein, coenzyme F420 biosynthesis associated.
 
    0.669
ADU48498.1
Hypothetical protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
  
     0.626
ADU49035.1
Hypothetical protein; COGs: COG3571 hydrolase of the alpha/beta-hydrolase fold; KEGG: gob:Gobs_4921 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.625
ADU49036.1
Protein of unknown function DUF159; COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: kse:Ksed_14680 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, COG2135; Belongs to the SOS response-associated peptidase family.
       0.625
ADU48749.1
GCN5-related N-acetyltransferase; COGs: COG3393 acetyltransferase; InterPro IPR016794: IPR000182; KEGG: kse:Ksed_11380 predicted acyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
     0.551
pup
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
  
     0.534
ADU47542.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.512
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
   
    0.500
ADU48569.1
KEGG: kra:Krad_3338 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3052).
  
     0.497
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.