STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49036.1Protein of unknown function DUF159; COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: kse:Ksed_14680 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, COG2135; Belongs to the SOS response-associated peptidase family. (280 aa)    
Predicted Functional Partners:
ADU49035.1
Hypothetical protein; COGs: COG3571 hydrolase of the alpha/beta-hydrolase fold; KEGG: gob:Gobs_4921 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.844
rsgA
GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
 
   
 0.737
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
     
 0.699
ADU46868.1
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: gbr:Gbro_4728 integrase family protein; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: Putative transposase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family.
   
    0.637
xerC
Tyrosine recombinase XerC subunit; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
   
    0.637
ADU49033.1
Anti-sigma factor; InterPro IPR014295; KEGG: ace:Acel_0539 anti-sigma factor; SPTR: Anti-sigma factor; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family.
       0.625
ADU49034.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014293: IPR014284: IPR007627: IPR013249; KEGG: art:Arth_2651 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02947 family.
       0.625
ADU49037.1
DoxX family protein; InterPro IPR011637; KEGG: rha:RHA1_ro00971 hypothetical protein; PFAM: DoxX family protein; SPTR: Putative uncharacterized protein; PFAM: DoxX.
       0.502
ADU49011.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: gob:Gobs_4282 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain.
  
    0.494
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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