Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADU49037.1DoxX family protein; InterPro IPR011637; KEGG: rha:RHA1_ro00971 hypothetical protein; PFAM: DoxX family protein; SPTR: Putative uncharacterized protein; PFAM: DoxX. (172 aa)    
Predicted Functional Partners:
rsgA
GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
 
     0.848
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.828
ADU48027.1
KEGG: cai:Caci_1654 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.520
ADU49036.1
Protein of unknown function DUF159; COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: kse:Ksed_14680 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, COG2135; Belongs to the SOS response-associated peptidase family.
       0.502
ADU49034.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014293: IPR014284: IPR007627: IPR013249; KEGG: art:Arth_2651 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02947 family.
  
    0.498
ADU49035.1
Hypothetical protein; COGs: COG3571 hydrolase of the alpha/beta-hydrolase fold; KEGG: gob:Gobs_4921 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.496
ADU47129.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR008250: IPR005834: IPR018303: IPR001757: IPR 000695; KEGG: nml:Namu_2937 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: ATPase, P-type (Transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamil [...]
   
  0.457
ADU49806.1
KEGG: saq:Sare_3577 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029).
  
    0.457
ADU50012.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR004014: IPR008250: IPR005834: IPR006068: IPR 001757: IPR000695: IPR018303; KEGG: bcv:Bcav_4202 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: ATPase, P-type (Transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, [...]
   
  0.457
ADU49033.1
Anti-sigma factor; InterPro IPR014295; KEGG: ace:Acel_0539 anti-sigma factor; SPTR: Anti-sigma factor; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family.
     
 0.448
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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