STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU49053.1KEGG: cms:CMS_1890 hypothetical protein; SPTR: Putative uncharacterized protein. (339 aa)    
Predicted Functional Partners:
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.788
ADU49048.1
COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: scb:SCAB_30561 putative MoaE-like protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin biosynthesis protein E; PFAM: MoaE protein.
  
 0.764
ADU47918.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: mmi:MMAR_0719 thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
 
 0.740
ADU49054.1
ABC-1 domain-containing protein; COGs: COG0661 unusual protein kinase; InterPro IPR000719: IPR004147: IPR002575; KEGG: kfl:Kfla_5331 ABC-1 domain protein; PFAM: ABC-1 domain-containing protein; aminoglycoside phosphotransferase; SPTR: Putative ABC transporter ATP-binding protein; PFAM: ABC1 family.
 
     0.688
ADU48452.1
KEGG: kra:Krad_1551 DNA-binding protein; SPTR: Putative DNA-binding protein; PFAM: Protein of unknown function (DUF3071).
 
     0.673
ADU48203.1
COGs: COG3429 Glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: kra:Krad_2925 OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; SPTR: OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein.
  
     0.659
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.628
ADU48487.1
KEGG: kfl:Kfla_2801 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
   0.626
ADU48076.1
KEGG: sen:SACE_5253 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
 0.598
ADU49559.1
Peptidase M12A astacin; InterPro IPR006026: IPR001506: IPR007280; KEGG: lch:Lcho_4313 peptidase domain-containing protein; PFAM: peptidase M12A astacin; peptidase domain protein; SMART: peptidase metallopeptidase; SPTR: Peptidase domain protein; PFAM: Astacin (Peptidase family M12A).
 
    0.583
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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