STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49067.1Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: sgr:SGR_2355 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Putative tetR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family. (229 aa)    
Predicted Functional Partners:
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
 
   
 0.640
ADU49068.1
KEGG: ske:Sked_27680 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3107).
       0.603
ADU49064.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1171 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: Putative ATP-dependent DNA helicase; PFAM: UvrD/REP helicase.
 
     0.557
ADU49065.1
Methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein; COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048: IPR004360; KEGG: cfl:Cfla_0254 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain.
       0.544
ADU47764.1
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: art:Arth_1285 putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; PRIAM: Adenylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylyl cyclase class-3/4/guanylyl cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
  
     0.509
ADU47019.1
Arsenite efflux ATP-binding protein ArsA; COGs: COG0003 ATPase involved in chromosome partitioning; KEGG: kfl:Kfla_0448 anion-transporting ATPase; SPTR: Putative uncharacterized protein; PFAM: Anion-transporting ATPase; TC 3.A.4.1.1.
  
     0.487
ADU48894.1
InterPro IPR002629; KEGG: tcu:Tcur_3565 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase vitamin-B12 independent; SPTR: Putative uncharacterized protein; PFAM: Cobalamin-independent synthase, Catalytic domain.
  
 
   0.481
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.