STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49072.1Cobyrinic acid a,c-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: nca:Noca_1467 cobyrinic acid a,c-diamide synthase; SPTR: Possible soj/para-related protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (267 aa)    
Predicted Functional Partners:
ADU50118.1
Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115: IPR004437; KEGG: cfl:Cfla_3719 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Putative ParB-like protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
 
 
 0.940
ADU49074.1
Hypothetical protein; InterPro IPR000276; KEGG: fal:FRAAL6067 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800).
     
 0.695
ADU49073.1
KEGG: sna:Snas_3837 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain.
       0.694
ADU48688.1
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593: IPR002543: IPR018541; KEGG: kse:Ksed_18080 DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Putative DNA translocase FtsK; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
  
 0.659
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.611
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.560
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.532
ADU47403.1
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nca:Noca_0602 phage integrase family protein; PFAM: integrase family protein; SPTR: Phage integrase family protein; PFAM: Phage integrase family.
 
   
 0.474
xerC
Tyrosine recombinase XerC subunit; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.463
ADU49076.1
PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141: IPR004013; KEGG: xce:Xcel_0771 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Putative uncharacterized protein; PFAM: PHP domain.
       0.449
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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