STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49076.1PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141: IPR004013; KEGG: xce:Xcel_0771 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Putative uncharacterized protein; PFAM: PHP domain. (305 aa)    
Predicted Functional Partners:
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
    
 0.905
ADU49077.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014325: IPR014284: IPR007627: IPR013249; KEGG: cfl:Cfla_2179 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: Putative RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polym [...]
       0.538
ADU49074.1
Hypothetical protein; InterPro IPR000276; KEGG: fal:FRAAL6067 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2800).
       0.536
ADU49078.1
Hypothetical protein; KEGG: azl:AZL_e00660 filamentous haemagglutinin outer membrane protein; SPTR: Putative uncharacterized protein.
       0.529
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
 
     0.515
ADU49073.1
KEGG: sna:Snas_3837 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain.
       0.487
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
     0.464
ADU48319.1
COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070: IPR004388; KEGG: ami:Amir_4990 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Putative uncharacterized protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
 
    0.454
ADU49072.1
Cobyrinic acid a,c-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: nca:Noca_1467 cobyrinic acid a,c-diamide synthase; SPTR: Possible soj/para-related protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.449
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
       0.446
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.