Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49080.1MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_1459 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain. (180 aa)    
Predicted Functional Partners:
ADU48925.1
COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR010085: IPR013154: IPR013149; KEGG: scb:SCAB_17621 crotonyl CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Crotonyl CoA reductase; TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: crotonyl-CoA reductase.
 
 
 0.743
ADU49092.1
HpcH/HpaI aldolase; COGs: COG2301 Citrate lyase beta subunit; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0079 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; SPTR: Citrate lyase, beta subunit, putative; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.659
ADU48932.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098: IPR006159: IPR006158: IPR006099; KEGG: gob:Gobs_4128 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Coenzyme B12-dependent mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
 
  
 0.621
ADU49091.1
COGs: COG2301 Citrate lyase beta subunit; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0078 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: Citrate lyase beta chain; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.618
ADU49888.1
Catalase; COGs: COG0753 Catalase; InterPro IPR018028: IPR010582: IPR011614: IPR002226; KEGG: sco:SCO0379 catalase; PFAM: Catalase related subgroup; Catalase domain protein; PRIAM: Catalase; SPTR: Catalase; PFAM: Catalase; Catalase-related immune-responsive; Belongs to the catalase family.
   
 0.610
ADU48928.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108; KEGG: kfl:Kfla_5009 3-hydroxyacyl-CoA dehydrogenase., 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; PRIAM: 3-hydroxybutyryl-CoA dehydrogenase., 3-hydroxybutyryl-CoA epimerase; SPTR: Putative 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 
 0.567
ADU49084.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: kfl:Kfla_5397 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 0.550
ADU48425.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.538
ADU49081.1
Protein of unknown function DUF1212; COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: kse:Ksed_19250 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF1212).
       0.525
ADU49079.1
KEGG: rha:RHA1_ro05202 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.506
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.