Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADU49081.1Protein of unknown function DUF1212; COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: kse:Ksed_19250 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF1212). (486 aa)    
Predicted Functional Partners:
ADU47307.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...]
     
 0.697
ADU49079.1
KEGG: rha:RHA1_ro05202 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.547
ADU49082.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865: IPR000994: IPR001131; KEGG: saq:Sare_0543 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: Aminopeptidase P; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
       0.546
ADU49080.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_1459 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain.
       0.525
ADU49049.1
COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: kse:Ksed_19090 hypothetical protein; PFAM: Protein of unknown function DUF2342; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: putative hydrolase.
 
     0.496
ADU49027.1
F420-dependent oxidoreductase; COGs: COG1478 conserved hypothetical protein; InterPro IPR008225: IPR002847; KEGG: kra:Krad_3852 F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129; SPTR: Putative uncharacterized protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: F420-0:Gamma-glutamyl ligase; TIGRFAM: F420-0:gamma-glutamyl ligase.
  
     0.487
ADU46972.1
GCN5-related N-acetyltransferase; COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: kfl:Kfla_4406 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
 
     0.461
ADU49405.1
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
     0.460
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.458
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.440
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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