STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49081.1Protein of unknown function DUF1212; COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: kse:Ksed_19250 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF1212). (486 aa)    
Predicted Functional Partners:
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.614
ADU48130.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Putative RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.567
ADU49082.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865: IPR000994: IPR001131; KEGG: saq:Sare_0543 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: Aminopeptidase P; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
       0.550
ADU49079.1
KEGG: rha:RHA1_ro05202 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.547
ADU46624.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 017441: IPR008271: IPR000719; KEGG: kra:Krad_0072 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Tyrosine protein kinase:Serine/threonine protein kinase:PASTA; PFAM: Protein kinase domain; PASTA domain.
       0.532
ADU47757.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR008271: IPR000719: IPR 020635: IPR002290; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain.
       0.532
ADU48474.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 008271: IPR000719; KEGG: nca:Noca_3086 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine kinase; PFAM: Protein kinase domain; PASTA domain.
       0.532
ADU49080.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_1459 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain.
       0.529
ADU49405.1
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
     0.521
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
    0.501
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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