STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49091.1COGs: COG2301 Citrate lyase beta subunit; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0078 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: Citrate lyase beta chain; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. (301 aa)    
Predicted Functional Partners:
ADU48932.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098: IPR006159: IPR006158: IPR006099; KEGG: gob:Gobs_4128 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Coenzyme B12-dependent mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
 
  
 0.740
ADU49092.1
HpcH/HpaI aldolase; COGs: COG2301 Citrate lyase beta subunit; InterPro IPR011206: IPR005000; KEGG: amd:AMED_0079 citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase; SPTR: Citrate lyase, beta subunit, putative; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
 
    
0.718
ADU49080.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: nca:Noca_1459 dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: MaoC domain protein dehydratase; PFAM: MaoC like domain.
 
  
 0.614
ADU46698.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Car [...]
  
  
 0.599
ADU49625.1
COGs: COG3777 conserved hypothetical protein; KEGG: mav:MAV_3005 MaoC like domain-containing protein; SPTR: MaoC like domain protein.
  
  
 0.574
ADU48925.1
COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR010085: IPR013154: IPR013149; KEGG: scb:SCAB_17621 crotonyl CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Crotonyl CoA reductase; TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: crotonyl-CoA reductase.
 
  
 0.558
ADU49201.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.550
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
   
  
 0.541
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
 
   
 0.521
ADU49642.1
FAD dependent oxidoreductase; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076; KEGG: nca:Noca_0198 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: FAD dependent oxidoreductase; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain.
 
    0.518
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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