STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49097.1Twin-arginine translocation protein, TatB subunit; InterPro IPR018448: IPR003998; KEGG: rsa:RSal33209_1193 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase TatB. (114 aa)    
Predicted Functional Partners:
tatC
Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
  
 
 0.963
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.925
ADU46620.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: xce:Xcel_0012 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; PFAM: Rhomboid family.
  
 
 0.721
tatA
Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
     
 0.686
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
   
  
 0.674
ADU49098.1
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_2919 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; SPTR: Putative protease; PFAM: Trypsin.
  
    0.674
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.668
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
  
 0.658
ADU49100.1
RNA polymerase, sigma 29 subunit, SigE; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: tbi:Tbis_3014 ECF subfamily RNA polymerase sigma-24; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Putative ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
       0.619
ADU48495.1
Menaquinol-cytochrome c reductase iron-sulfur subunit precursor; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: kse:Ksed_16200 Rieske Fe-S protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulphur component of ubiQ-cytB reductase; PFAM: Rieske [2Fe-2S] domain.
 
  
 0.615
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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