STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49100.1RNA polymerase, sigma 29 subunit, SigE; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: tbi:Tbis_3014 ECF subfamily RNA polymerase sigma-24; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Putative ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (229 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.849
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.849
ADU49422.1
COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: kra:Krad_0898 transcriptional regulator, CarD family; PFAM: transcription factor CarD; SPTR: Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain.
    
   0.846
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.758
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.758
ADU49098.1
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_2919 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; SPTR: Putative protease; PFAM: Trypsin.
  
  
 0.692
ADU48650.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014325: IPR014284; KEGG: ace:Acel_0787 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: Putative RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymera [...]
  
     0.669
ADU47542.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: sgr:SGR_2758 RNA polymerase sigma factor SigD; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma 32 subunit, RpoH; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.666
ADU47198.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR007630: IPR014284; KEGG: sma:SAV_4735 ECF subfamily RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02952 family.
  
     0.664
ADU49099.1
KEGG: ssl:SS1G_03268 hypothetical protein; SPTR: Predicted protein.
       0.652
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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