Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
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gene co-occurrence
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ADU49118.1GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225: IPR006298: IPR000795: IPR004161: IPR 000640; KEGG: sro:Sros_7974 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Small GTP-binding protein domain:GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein T [...] (632 aa)    
Predicted Functional Partners:
ADU49117.1
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: nca:Noca_2400 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Putative ABC transporter solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
  
    0.823
ADU49119.1
NUDIX hydrolase; InterPro IPR020476: IPR000086: IPR020084; KEGG: xce:Xcel_0048 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: Putative mutT-like protein; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein.
       0.803
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.787
ADU49116.1
1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-gluc opyranosidedeacetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR017810: IPR003737; KEGG: sma:SAV_3138 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; PFAM: LmbE family protein; SPTR: Putative N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D -glucopyranosidedeacetylase; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Belongs to [...]
       0.739
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.673
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.671
tsf
Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.610
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: krh:KRH_06470 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
  
    0.610
ADU47439.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: kse:Ksed_03410 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding subunit; PFAM: ABC transporter.
 
   
 0.603
infC
Bacterial translation initiation factor 3 (bIF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
 
 0.602
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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