STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU49149.1Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: bbr:BB0876 polysaccharide biosynthesis protein; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative lipopolysaccharide biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose [...] (441 aa)    
Predicted Functional Partners:
ADU49778.1
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: krh:KRH_12670 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 
 0.960
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.921
ADU49142.1
UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025: IPR003869; KEGG: kfl:Kfla_0497 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein CapD; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase.
  
 
 0.919
ADU49773.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterProIPR016160: IPR017476: IPR001732: IPR014026: IPR 014027; KEGG: kse:Ksed_26760 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrog [...]
  
  
 
0.919
ADU48427.1
COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001387: IPR001986; KEGG: scb:SCAB_21131 putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Helix-turn-helix; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
    
  0.906
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
  0.902
ADU49148.1
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: cgb:cg0418 putative aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.849
ADU49147.1
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: cgb:cg0419 glycosyltransferase; PFAM: sugar transferase; SPTR: Glycosyltransferase; PFAM: Bacterial sugar transferase.
  
    0.815
ADU49150.1
COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: rhi:NGR_c19670 probable lipopolysaccharide modification acyltransferase; PFAM: acyltransferase 3; SPTR: Probable lipopolysaccharide modification acyltransferase; manually curated; PFAM: Acyltransferase family.
  
    0.793
ADU49151.1
Polysaccharide biosynthesis protein CapD; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: rsa:RSal33209_1438 UDP-D-quinovosamine 4-dehydrogenase; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Probable dtdp-glucose 4,6-dehydratase transmembrane protein; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.681
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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