STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49153.1Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: nfa:nfa24980 putative transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Putative transcriptional regulator; PFAM: HxlR-like helix-turn-helix. (222 aa)    
Predicted Functional Partners:
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
  
 0.781
ADU48766.1
KEGG: cmi:CMM_1413 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.751
ADU49281.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR017685; KEGG: xce:Xcel_2242 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family.
   
  
 0.749
ADU49307.1
Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: rop:ROP_12400 putative MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Putative transcriptional regulator; PFAM: MarR family.
   
  
 0.749
ADU46779.1
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family.
   
    0.731
ADU48216.1
COGs: COG2345 transcriptional regulator protein; KEGG: kse:Ksed_13330 predicted transcriptional regulator; SPTR: Putative DNA-binding protein; PFAM: HTH domain.
   
    0.731
ADU49152.1
KEGG: scl:sce6047 protein kinase.
       0.714
ADU49154.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rha:RHA1_ro02392 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase; PFAM: Methyltransferase domain.
 
     0.712
ADU48665.1
KEGG: xce:Xcel_2206 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: PemK-like protein.
   
    0.677
ADU48634.1
Zinc uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mmi:MMAR_3669 zinc uptake regulation protein Zur; PFAM: ferric-uptake regulator; SPTR: Zinc uptake regulation protein Zur; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
   
  
 0.558
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.