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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49154.1Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rha:RHA1_ro02392 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase; PFAM: Methyltransferase domain. (274 aa)    
Predicted Functional Partners:
ADU49153.1
Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: nfa:nfa24980 putative transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Putative transcriptional regulator; PFAM: HxlR-like helix-turn-helix.
 
     0.712
ADU49155.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: nml:Namu_1402 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold.
 
     0.611
ADU46977.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: nca:Noca_2043 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Putative methyltransferase, S-Adenosyl-L-methionine (SAM)-MTase protein; PFAM: Methyltransferase domain.
  
     0.522
ADU48130.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Putative RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
     
 0.490
ADU49152.1
KEGG: scl:sce6047 protein kinase.
       0.484
ADU47595.1
Regulatory protein MarR; InterPro IPR000835; KEGG: nca:Noca_0115 regulatory protein, MarR; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Putative uncharacterized protein; PFAM: MarR family.
     
 0.457
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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