STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU49167.1Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792; KEGG: vap:Vapar_3549 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Putative uncharacterized protein; PFAM: Archaeal ATPase; Bacterial regulatory proteins, luxR family. (978 aa)    
Predicted Functional Partners:
ADU49815.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain.
 
 
 0.730
ADU49829.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR004358: IPR003594: IPR017205: IPR 011712; KEGG: sco:SCO1369 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Probable two component system histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.712
ADU49498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR013767: IPR011712; KEGG: nca:Noca_2942 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.709
ADU48392.1
COGs: COG3850 Signal transduction histidine kinase nitrate/nitrite-specific; InterPro IPR011712: IPR003594: IPR005467; KEGG: ttr:Tter_2549 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.707
ADU49308.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000595: IPR003594: IPR005467: IPR004358; KEGG: rha:RHA1_ro04003 sensor kinase, two-component system; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.637
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.635
ADU47497.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: bcv:Bcav_3033 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; SPTR: Putative two-component system DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
  
     0.615
ADU47485.1
Putative hydrolase and adenylate/guanylate cyclase; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000073: IPR001054; KEGG: mav:MAV_5228 hydrolase, alpha/beta hydrolase fold family protein; PFAM: alpha/beta hydrolase fold; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Hydrolase, alpha/beta hydrolase fold family protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; alpha/beta hydrolase fold.
 
 
 0.558
ADU49168.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR012951: IPR006093; KEGG: gob:Gobs_3657 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; SPTR: FAD linked oxidase; PFAM: Berberine and berberine like; FAD binding domain.
       0.523
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
 
 
 0.496
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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