STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49196.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tpr:Tpau_0525 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Putative uncharacterized protein; PFAM: pfkB family carbohydrate kinase. (317 aa)    
Predicted Functional Partners:
ADU49195.1
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: kfl:Kfla_5587 fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: Putative fructose-1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
    
 0.980
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
    
 0.946
ADU48602.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: kfl:Kfla_1360 mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
  
 0.931
ADU47873.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: cfl:Cfla_2176 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Putative alpha-glucosidase; PFAM: Alpha amylase, catalytic domain.
 
 
 0.921
ADU49018.1
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase; InterPro IPR019490: IPR006162; KEGG: kra:Krad_3839 putative transcriptional regulator, RpiR family; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; SPTR: Putative uncharacterized protein; PFAM: Bacterial phospho-glucose isomerase C-terminal region.
  
 
 0.919
pfkA
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.916
ADU48205.1
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: ach:Achl_1836 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.912
ADU46999.1
COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: bcv:Bcav_3837 alpha-glucosidase; PFAM: glycoside hydrolase family 31; PRIAM: Alpha-glucosidase; SPTR: Alpha-glucosidase; PFAM: Glycosyl hydrolases family 31; Belongs to the glycosyl hydrolase 31 family.
  
 
 0.908
ADU49407.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006589: IPR006047; KEGG: sro:Sros_3328 maltodextrin glucosidase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Maltodextrin glucosidase; PFAM: Alpha amylase, catalytic domain.
   
 0.905
ADU47469.1
Glutamine--fructose-6-phosphate transaminase; COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: kra:Krad_0771 glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine--fructose-6-phosphate transaminase (Isomerizing); PFAM: SIS domain.
     
 0.902
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.