STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49281.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR017685; KEGG: xce:Xcel_2242 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family. (292 aa)    
Predicted Functional Partners:
ADU49282.1
Lysine exporter protein (LYSE/YGGA); COGs: COG1279 Lysine efflux permease; InterPro IPR001123; KEGG: rha:RHA1_ro03597 lysine exporter protein; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein; PFAM: LysE type translocator; TIGRFAM: L-lysine exporter.
 
   
 0.960
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
    0.763
ADU49153.1
Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: nfa:nfa24980 putative transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Putative transcriptional regulator; PFAM: HxlR-like helix-turn-helix.
   
  
 0.749
ADU48216.1
COGs: COG2345 transcriptional regulator protein; KEGG: kse:Ksed_13330 predicted transcriptional regulator; SPTR: Putative DNA-binding protein; PFAM: HTH domain.
   
    0.727
ADU48766.1
KEGG: cmi:CMM_1413 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.674
ADU49351.1
DNA binding domain protein, excisionase family; InterPro IPR010093; KEGG: mbt:JTY_0764 putative transcriptional regulatory protein; SPTR: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN; TIGRFAM: DNA binding domain protein, excisionase family; manually curated; TIGRFAM: DNA binding domain, excisionase family.
   
    0.627
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.586
ADU47009.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: mkm:Mkms_4430 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
  
 0.570
ADU46903.1
Putative transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR011663; KEGG: nda:Ndas_2625 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain-containing protein; SPTR: Transcriptional regulator, GntR family; manually curated; PFAM: UTRA domain.
   
  
 0.562
ADU46779.1
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family.
   
  
 0.555
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.