STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49320.1Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963: IPR006656: IPR006657; KEGG: nca:Noca_2934 formate dehydrogenase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (963 aa)    
Predicted Functional Partners:
ADU49321.1
Polysulphide reductase NrfD; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896: IPR005614: IPR017900; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Polysulphide reductase NrfD; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; Polysulphide reductase, NrfD.
 
 
 0.999
ADU48494.1
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome c, mono- and diheme variants family; PFAM: cytochrome c class I; SPTR: Cytochrome C heme-binding subunit; PFAM: Cytochrome c.
  
 
 0.909
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.909
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.871
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.862
ADU48380.1
COGs: COG3005 Nitrate/TMAO reductase membrane-bound tetraheme cytochrome c subunit; InterPro IPR017571: IPR011031; KEGG: ahe:Arch_1475 cytochrome c nitrate reductase, small subunit; SPTR: Cytochrome c nitrate reductase, small subunit; TIGRFAM: cytochrome c nitrate reductase, small subunit; PFAM: NapC/NirT cytochrome c family, N-terminal region; TIGRFAM: cytochrome c nitrate reductase, small subunit.
  
 0.821
ADU49319.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.778
ADU46997.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase.
  
 
 0.746
ADU49322.1
SirA-like domain-containing protein; InterPro IPR001455; KEGG: nca:Noca_2932 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.
     
 0.743
ADU48495.1
Menaquinol-cytochrome c reductase iron-sulfur subunit precursor; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: kse:Ksed_16200 Rieske Fe-S protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulphur component of ubiQ-cytB reductase; PFAM: Rieske [2Fe-2S] domain.
  
 
 0.671
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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