STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49321.1Polysulphide reductase NrfD; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896: IPR005614: IPR017900; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Polysulphide reductase NrfD; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; Polysulphide reductase, NrfD. (508 aa)    
Predicted Functional Partners:
ADU49320.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963: IPR006656: IPR006657; KEGG: nca:Noca_2934 formate dehydrogenase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.999
ADU48145.1
Hypothetical protein; InterPro IPR017517: IPR017519; KEGG: saq:Sare_3408 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: conserved hypothetical protein TIGR03085; uncharacterized Actinobacterial protein TIGR03083.
  
 
 0.976
ADU48494.1
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome c, mono- and diheme variants family; PFAM: cytochrome c class I; SPTR: Cytochrome C heme-binding subunit; PFAM: Cytochrome c.
  
 
 0.953
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.915
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.876
ADU49322.1
SirA-like domain-containing protein; InterPro IPR001455; KEGG: nca:Noca_2932 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.
 
 
 
 0.870
ADU48379.1
COGs: COG3303 Formate-dependent nitrite reductase periplasmic cytochrome c552 subunit; InterPro IPR003321: IPR011031; KEGG: ahe:Arch_1474 nitrite reductase (cytochrome; ammonia-forming); PFAM: cytochrome c552; PRIAM: Nitrite reductase (cytochrome; ammonia-forming); SPTR: Nitrite reductase (Cytochrome; ammonia-forming); PFAM: Cytochrome c552; Belongs to the cytochrome c-552 family.
  
  
 0.801
ADU49323.1
NADH dehydrogenase; COGs: COG2210 conserved hypothetical protein; KEGG: rha:RHA1_ro11228 NADH dehydrogenase; SPTR: Possible NADH dehydrogenase.
 
     0.764
ADU47311.1
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006963: IPR006656: IPR006657: IPR006655; KEGG: art:Arth_4046 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.760
ADU49506.1
COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR020396; KEGG: tcu:Tcur_4707 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
  
  
 0.734
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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