STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49332.1Peptidase S58 DmpA; COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321: IPR002202; KEGG: sro:Sros_2464 aminopeptidase; PFAM: peptidase S58 DmpA; SPTR: Aminopeptidase; PFAM: Peptidase family S58. (355 aa)    
Predicted Functional Partners:
ADU49333.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: cfl:Cfla_3552 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.541
ADU49334.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: sco:SCO5872 turgor pressure regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Turgor pressure regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.541
ADU47575.1
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: sro:Sros_4594 putative secreted protein; PFAM: Amidohydrolase 3; SPTR: Putative secreted protein; PFAM: Amidohydrolase family.
  
     0.506
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.