STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49337.1InterPro IPR013096; KEGG: pfr:PFREUD_02140 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain. (113 aa)    
Predicted Functional Partners:
ADU46903.1
Putative transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR011663; KEGG: nda:Ndas_2625 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain-containing protein; SPTR: Transcriptional regulator, GntR family; manually curated; PFAM: UTRA domain.
  
  
 0.676
ADU47584.1
Transcriptional regulator, ArsR family; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001845: IPR001763: IPR001307; KEGG: sen:SACE_4409 ArsR family transcriptional regulator; PFAM: Rhodanese domain protein; regulatory protein ArsR; SMART: Rhodanese domain protein; regulatory protein ArsR; SPTR: Possible transcriptional regulatory protein (Possibly ArsR-family); PFAM: Bacterial regulatory protein, arsR family; Rhodanese-like domain.
  
  
 0.540
ADU48582.1
Transcriptional regulator, ArsR family; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001845: IPR001763; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; Rhodanese domain protein; SMART: regulatory protein ArsR; Rhodanese domain protein; SPTR: Possible transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family; Rhodanese-like domain.
  
  
 0.540
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
    0.528
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.504
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
    0.480
ADU49336.1
KEGG: bcv:Bcav_1591 glycoside hydrolase family 2 sugar binding; SPTR: Glycoside hydrolase family 2 sugar binding; PFAM: Protein of unknown function (DUF2804).
       0.463
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.426
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.