STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49347.1InterPro IPR004155; KEGG: xac:XAC1869 hypothetical protein; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT domain protein repeat-containing protein. (246 aa)    
Predicted Functional Partners:
efp
Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.951
ADU49348.1
YD repeat protein; InterPro IPR003587: IPR006141: IPR006530; KEGG: stp:Strop_1054 YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: YD repeat protein; TIGRFAM: YD repeat protein; PFAM: Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain.
     
 0.804
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.574
ADU48276.1
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: cfl:Cfla_2005 tRNA (adenine-N(1)-)-methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: Putative uncharacterized protein; PFAM: tRNA methyltransferase complex GCD14 subunit.
   
    0.493
nuoH
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
    0.479
nuoH-2
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
    0.479
ADU49349.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: mtp:Mthe_1139 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel proteins; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
    0.473
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
   0.450
ADU48509.1
Iron-sulfur cluster assembly accessory protein; COGs: COG0316 conserved hypothetical protein; InterPro IPR000361: IPR016092: IPR017870; KEGG: kra:Krad_3261 iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: Putative uncharacterized protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
    
 
 0.431
ADU49040.1
HesB/YadR/YfhF-family protein; InterPro IPR000361; KEGG: xce:Xcel_0286 HesB/YadR/YfhF-family protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: HesB/YadR/YfhF-family protein; PFAM: Iron-sulphur cluster biosynthesis.
    
 
 0.431
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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