STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49350.1Glutathione-independent formaldehyde dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, gl [...] (404 aa)    
Predicted Functional Partners:
ADU48711.1
KEGG: mno:Mnod_0253 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: NADH-dependant formate dehydrogenase delta subunit FdsD.
     
 0.903
ADU48708.1
Formate dehydrogenase, gamma subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; KEGG: msm:MSMEG_0159 formate dehydrogenase, gamma subunit; SPTR: Formate dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
    
 0.902
ADU47389.1
Glutathione-independent formaldehyde dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, gl [...]
  
  
 
0.900
ADU48709.1
Formate dehydrogenase beta subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: msm:MSMEG_0160 formate dehydrogenase, beta subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH oxidoreductase (Quinone), F subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB [...]
    
  0.900
ADU48710.1
Formate dehydrogenase alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR006478: IPR017900: IPR006655: IPR001041: IPR 017896: IPR019574: IPR006963: IPR006656: IPR006657; KEGG: msm:MSMEG_0161 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopt [...]
     
  0.900
ADU49349.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: mtp:Mthe_1139 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel proteins; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
   0.691
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.539
ADU49347.1
InterPro IPR004155; KEGG: xac:XAC1869 hypothetical protein; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT domain protein repeat-containing protein.
       0.407
ADU49348.1
YD repeat protein; InterPro IPR003587: IPR006141: IPR006530; KEGG: stp:Strop_1054 YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: YD repeat protein; TIGRFAM: YD repeat protein; PFAM: Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain.
       0.407
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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