STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU49354.1NUDIX hydrolase; InterPro IPR000086; KEGG: kse:Ksed_21710 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain. (270 aa)    
Predicted Functional Partners:
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.964
ADU48556.1
COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: kse:Ksed_12120 exoribonuclease R; PFAM: ribonuclease II; SPTR: Putative ribonuclease R; PFAM: RNB domain.
 
 
 0.852
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.778
ADU49355.1
KEGG: cms:CMS_2757 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Proteins of 100 residues with WXG; Belongs to the WXG100 family.
 
     0.708
ADU46785.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR014021: IPR 014014; KEGG: nca:Noca_4567 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
 0.574
deaD
ATP-dependent RNA helicase CsdA; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
 0.574
ADU47823.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR014021: IPR 014014; KEGG: kse:Ksed_10490 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
   
 0.574
ADU49071.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR014001: IPR 011545: IPR000629; KEGG: ske:Sked_27750 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
   
 0.574
ADU48056.1
KEGG: aau:AAur_1609 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.531
ADU49353.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR001891: IPR002912: IPR012301: IPR012302; KEGG: nca:Noca_2034 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
       0.526
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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