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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (141 aa)    
Predicted Functional Partners:
ADU49434.1
Asparaginase; COGs: COG4448 L-asparaginase II; InterPro IPR010349; KEGG: kse:Ksed_03610 L-asparaginase II; PFAM: L-asparaginase II; SPTR: Putative uncharacterized protein; PFAM: L-asparaginase II.
       0.832
ADU49432.1
Protein of unknown function DUF2516; InterPro IPR019662; KEGG: kra:Krad_0886 putative integral membrane protein; PFAM: Protein of unknown function DUF2516; SPTR: Putative integral membrane protein; PFAM: Protein of unknown function (DUF2516).
       0.752
ADU49436.1
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: tcu:Tcur_0663 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative DNA-binding protein; PFAM: Helix-turn-helix.
       0.707
ADU49435.1
KEGG: tpr:Tpau_0881 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.702
ADU48362.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.535
ADU49431.1
COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: kse:Ksed_18490 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase.
       0.529
ADU47303.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E (SpoIIE); MASE1.
       0.485
ADU49439.1
Folate-binding protein YgfZ; COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR006222: IPR013977: IPR017703; KEGG: kse:Ksed_03590 folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; SPTR: Putative uncharacterized protein; TIGRFAM: folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ; Belongs to the GcvT family.
  
    0.480
ADU49437.1
KEGG: eat:EAT1b_1071 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.466
ADU49440.1
Domain of unknown function DUF1794; May play a role in the intracellular transport of hydrophobic ligands.
       0.435
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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