STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49443.1thiamineS protein; InterPro IPR003749; KEGG: mmi:MMAR_4664 molybdenum cofactor biosynthesis protein D 2 MoaD2; PFAM: thiamineS protein; SPTR: Putative molybdopterin converting factor; PFAM: ThiS family. (101 aa)    
Predicted Functional Partners:
ADU49048.1
COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: scb:SCAB_30561 putative MoaE-like protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin biosynthesis protein E; PFAM: MoaE protein.
  
 0.996
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
  
 0.988
ADU48874.1
thiamineS protein; InterPro IPR003749; KEGG: aau:AAur_4051 ThiS family protein; PFAM: thiamineS protein; SPTR: ThiS family protein; PFAM: ThiS family.
     
  0.900
ADU47419.1
GTP cyclohydrolase subunit MoaC; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: gob:Gobs_4471 molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
  
  
 0.830
ADU49442.1
KEGG: ske:Sked_04940 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.788
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.681
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.666
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
       0.632
ADU49444.1
Putative two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: tcu:Tcur_0595 putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; SPTR: Transcriptional regulatory protein; PFAM: Transcriptional regulatory protein, C terminal.
 
     0.617
ADU47420.1
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR020817: IPR008284; KEGG: kfl:Kfla_5764 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Putative molybdopterin biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
  
 0.575
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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