Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADU49443.1thiamineS protein; InterPro IPR003749; KEGG: mmi:MMAR_4664 molybdenum cofactor biosynthesis protein D 2 MoaD2; PFAM: thiamineS protein; SPTR: Putative molybdopterin converting factor; PFAM: ThiS family. (101 aa)    
Predicted Functional Partners:
ADU49048.1
COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: scb:SCAB_30561 putative MoaE-like protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin biosynthesis protein E; PFAM: MoaE protein.
  
 0.996
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
  
 0.983
ADU48874.1
thiamineS protein; InterPro IPR003749; KEGG: aau:AAur_4051 ThiS family protein; PFAM: thiamineS protein; SPTR: ThiS family protein; PFAM: ThiS family.
     
  0.900
ADU47419.1
GTP cyclohydrolase subunit MoaC; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: gob:Gobs_4471 molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
  
  
 0.853
ADU49442.1
KEGG: ske:Sked_04940 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.787
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.711
ADU47420.1
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR020817: IPR008284; KEGG: kfl:Kfla_5764 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Putative molybdopterin biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
  
 0.674
ADU49444.1
Putative two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: tcu:Tcur_0595 putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; SPTR: Transcriptional regulatory protein; PFAM: Transcriptional regulatory protein, C terminal.
 
     0.616
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
       0.608
ADU49053.1
KEGG: cms:CMS_1890 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.496
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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