STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshDMycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (303 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
      0.953
mshC
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
  
 0.904
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
   
 0.878
ADU49444.1
Putative two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: tcu:Tcur_0595 putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; SPTR: Transcriptional regulatory protein; PFAM: Transcriptional regulatory protein, C terminal.
       0.837
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.782
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
 
   0.775
ADU49116.1
1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-gluc opyranosidedeacetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR017810: IPR003737; KEGG: sma:SAV_3138 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; PFAM: LmbE family protein; SPTR: Putative N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside deacetylase; TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D -glucopyranosidedeacetylase; PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Belongs to [...]
  
   
 0.756
ADU47099.1
LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: kse:Ksed_25150 uncharacterized LmbE-like protein; PFAM: LmbE family protein; SPTR: Uncharacterized LmbE-like protein; PFAM: GlcNAc-PI de-N-acetylase.
  
   
 0.662
ADU49442.1
KEGG: ske:Sked_04940 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.643
ADU49747.1
Hypothetical protein; InterPro IPR014487; KEGG: kse:Ksed_05660 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3151).
  
     0.635
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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