STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49447.1COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR000086: IPR013078: IPR020084; KEGG: kse:Ksed_03520 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; Phosphoglycerate mutase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain; Phosphoglycerate mutase family. (316 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
   
 0.768
ADU49448.1
Phosphate ABC transporter substrate-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
     
 0.657
ADU49444.1
Putative two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: tcu:Tcur_0595 putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; SPTR: Transcriptional regulatory protein; PFAM: Transcriptional regulatory protein, C terminal.
     
 0.573
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
    0.572
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
 
   0.549
ADU47116.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593; KEGG: kse:Ksed_24860 DNA polymerase III, gamma/tau subunit; SMART: AAA ATPase; SPTR: ATPase; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit.
 
     0.542
ADU50105.1
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020476: IPR020084; KEGG: kse:Ksed_26900 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
  
     0.515
ADU48041.1
DivIVA domain; InterPro IPR019933: IPR007793; KEGG: cdi:DIP1590 antigen 84; PFAM: DivIVA family protein; SPTR: Wag31; TIGRFAM: DivIVA domain; TIGRFAM: DivIVA domain.
  
    0.496
ADU49449.1
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
       0.485
ADU49450.1
Phosphate ABC transporter membrane protein 2, PhoT family; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515: IPR005672; KEGG: kfl:Kfla_0961 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Putative phosphate transport system permease protein; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.
       0.485
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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