Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADU49490.1Protein of unknown function DUF2078, membrane; InterPro IPR018649; KEGG: rop:ROP_pROB01-02360 hypothetical membrane protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2078). (83 aa)    
Predicted Functional Partners:
ADU49489.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR017909: IPR011707: IPR001117: IPR011706: IPR 002355; KEGG: pfr:PFREUD_19350 multicopper oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase; PFAM: Multicopper oxidase; TIGRFAM: copper-resistance protein, CopA family.
 
     0.795
ADU49492.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: mlu:Mlut_18370 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His K [...]
 
     0.650
ADU49491.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: rha:RHA1_ro11203 response regulator, two-component system; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator, two-component system; manually curated; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.520
ADU49516.1
InterPro IPR018649; KEGG: rxy:Rxyl_3081 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2078).
  
     0.519
ADU47268.1
InterPro IPR004360; KEGG: rop:ROP_60000 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
  
     0.482
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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