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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49492.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: mlu:Mlut_18370 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His K [...] (381 aa)    
Predicted Functional Partners:
ADU49491.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: rha:RHA1_ro11203 response regulator, two-component system; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator, two-component system; manually curated; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.962
ADU49489.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR017909: IPR011707: IPR001117: IPR011706: IPR 002355; KEGG: pfr:PFREUD_19350 multicopper oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase; PFAM: Multicopper oxidase; TIGRFAM: copper-resistance protein, CopA family.
 
 
 0.870
ADU47305.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: rha:RHA1_ro11203 response regulator, two-component system; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator, two-component system; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.842
ADU49514.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: nca:Noca_3782 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.839
ADU47598.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: nca:Noca_2939 response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.784
ADU49424.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: kra:Krad_0896 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.757
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
 
 
0.742
ADU49173.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: mta:Moth_1478 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.742
ADU48779.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: sgr:SGR_2224 putative two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.737
ADU49014.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867: IPR005829; KEGG: scb:SCAB_55281 putative two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   0.737
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.