STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49509.1COGs: COG0650 Formate hydrogenlyase subunit 4; KEGG: nml:Namu_2986 respiratory-chain NADH dehydrogenase, subunit 1; SPTR: Respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH dehydrogenase. (319 aa)    
Predicted Functional Partners:
ADU49506.1
COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR020396; KEGG: tcu:Tcur_4707 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
 
 
 0.999
ADU49511.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: nml:Namu_2984 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.998
ADU49510.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918: IPR001750; KEGG: tcu:Tcur_4703 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
 
 0.992
ADU49507.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918: IPR001750; KEGG: tcu:Tcur_4706 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
 
 0.988
ADU49508.1
Hypothetical protein; COGs: COG4237 Hydrogenase 4 membrane component (E); KEGG: tcu:Tcur_4705 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.973
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.878
nuoI-2
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.878
ADU49512.1
InterPro IPR001845; KEGG: nml:Namu_2983 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family.
       0.773
nuoB-2
NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
   0.510
nuoB
NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
   0.499
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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