STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49553.1COGs: COG3239 Fatty acid desaturase; InterPro IPR005804; KEGG: art:Arth_0195 fatty acid desaturase; PFAM: fatty acid desaturase; SPTR: Fatty acid desaturase; PFAM: Fatty acid desaturase. (430 aa)    
Predicted Functional Partners:
ADU49552.1
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR001041: IPR017927: IPR001221: IPR008333: IPR 001433; KEGG: art:Arth_0194 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
 
 0.999
ADU49551.1
KEGG: art:Arth_0193 CdaR family transcriptional regulator; SPTR: Transcriptional regulator, CdaR family.
 
     0.818
ADU49554.1
HAD-superfamily subfamily IB hydrolase, TIGR01490; COGs: COG0560 Phosphoserine phosphatase; InterPro IPR005834: IPR006383: IPR006385; KEGG: cwo:Cwoe_4644 HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily subfamily IB hydrolase, TIGR01490; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like.
       0.788
ADU49864.1
COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR004792: IPR013027; KEGG: kfl:Kfla_5848 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; HI0933 family protein; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
 
   
 0.616
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
      
 0.604
menG
2-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
      
 0.581
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
  
  
 0.572
ADU48127.1
COGs: COG3268 conserved hypothetical protein; InterPro IPR005097; KEGG: gob:Gobs_2039 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; PRIAM: Saccharopine dehydrogenase (NAD(+), L-glutamate-forming); SPTR: Putative uncharacterized protein; PFAM: Saccharopine dehydrogenase.
  
    0.551
ADU48400.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: gob:Gobs_0307 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
  
 
 
 0.537
ADU48401.1
3-ketoacyl-CoA thiolase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155; KEGG: cwo:Cwoe_0195 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
   
 0.523
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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