Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49574.1KEGG: mar:MAE_46730 hypothetical protein; SPTR: Putative uncharacterized protein. (327 aa)    
Predicted Functional Partners:
ADU49573.1
KEGG: tel:tll1780 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.820
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.750
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.741
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.727
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.727
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.718
ADU49570.1
Helicase domain protein; InterPro IPR001650; KEGG: xce:Xcel_2322 helicase domain protein; PFAM: helicase domain protein; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain.
       0.552
ADU49572.1
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014021: IPR001650: IPR014001: IPR000330; KEGG: xce:Xcel_2324 helicase domain protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
       0.552
ADU49568.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ske:Sked_03300 hypothetical protein; SMART: phospholipase D/Transphosphatidylase; SPTR: Phospholipase D/Transphosphatidylase.
       0.547
ADU49569.1
Protein of unknown function DUF1998; InterPro IPR018973; KEGG: xce:Xcel_2321 hypothetical protein; PFAM: Protein of unknown function DUF1998; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1998).
       0.547
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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