STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49607.1Hypothetical protein; COGs: COG3505 Type IV secretory pathway VirD4 protein; KEGG: mlu:Mlut_00130 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: TraG/TraD family. (591 aa)    
Predicted Functional Partners:
ADU49608.1
KEGG: xce:Xcel_0797 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.915
ADU49594.1
KEGG: kse:Ksed_06740 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: TrbL/VirB6 plasmid conjugal transfer protein.
 
   
 0.893
ADU49596.1
Hypothetical protein; COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: mlu:Mlut_00150 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.871
ADU49595.1
KEGG: kse:Ksed_06750 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.856
ADU49581.1
TrwC relaxase; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR014862; KEGG: xce:Xcel_0849 TrwC relaxase; PFAM: TrwC relaxase; SPTR: TrwC relaxase; PFAM: TrwC relaxase; TIGRFAM: conjugative relaxase domain, TrwC/TraI family.
 
   
 0.826
ADU49592.1
KEGG: xce:Xcel_0821 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.797
ADU47845.1
KEGG: kse:Ksed_00460 HNH endonuclease; SPTR: HNH endonuclease.
 
 
 
 0.604
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.516
ADU49610.1
DNA primase catalytic core domain; COGs: COG0358 DNA primase; InterPro IPR002694: IPR013264; KEGG: fra:Francci3_1282 DNA primase; PFAM: DNA primase catalytic core domain; SPTR: DNA primase; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.
 
     0.489
ADU47971.1
HNH endonuclease; InterPro IPR002711: IPR003615; KEGG: kse:Ksed_09510 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease; Domain of unknown function DUF222.
 
 
 
 0.476
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.