STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49641.1COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR014757: IPR002563; KEGG: cgt:cgR_2302 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain. (416 aa)    
Predicted Functional Partners:
ADU49640.1
Regulatory protein TetR; InterPro IPR001647; KEGG: nca:Noca_0219 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; PFAM: Bacterial regulatory proteins, tetR family.
 
   
 0.582
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family.
  
  
 0.572
ADU49639.1
Regulatory protein TetR; InterPro IPR001647; KEGG: nca:Noca_0220 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; manually curated; PFAM: Bacterial regulatory proteins, tetR family.
 
   
 0.567
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.539
ADU49650.1
Acyl-CoA dehydrogenase type 2 domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mab:MAB_0075 putative hydroxylase; PFAM: Acyl-CoA dehydrogenase type 2 domain; SPTR: Putative hydroxylase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
 
  
 0.524
ADU49652.1
Acyl-CoA dehydrogenase type 2 domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mpa:MAP1448c hypothetical protein; PFAM: Acyl-CoA dehydrogenase type 2 domain; SPTR: Pigment production hydroxylase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
 
  
 0.523
ADU47353.1
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: svi:Svir_06200 conserved hypothetical protein TIGR00370; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Putative uncharacterized protein; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
  
    0.518
ADU47354.1
Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: kfl:Kfla_6553 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain.
  
    0.505
ADU48268.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.475
ADU47614.1
4-oxalocrotonate decarboxylase; COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mjl:Mjls_4208 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 4-oxalocrotonate decarboxylase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
  
 0.457
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.