Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49648.1Isocitrate lyase and phosphorylmutase; COGs: COG2513 PEP phosphonomutase; InterPro IPR000918; KEGG: nca:Noca_0204 2,3-dimethylmalate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: 2,3-dimethylmalate lyase; PFAM: Isocitrate lyase family. (315 aa)    
Predicted Functional Partners:
ADU47357.1
COGs: COG2225 Malate synthase; InterPro IPR011076: IPR006252: IPR019830; KEGG: kfl:Kfla_0722 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
 
 0.809
ADU49647.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: nca:Noca_0203 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; TIGRFAM: flavocytochrome c.
 
     0.808
ADU49646.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: nca:Noca_0202 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
  
  
 0.780
ADU49649.1
Glyoxalase/bleomycin resistance protein/dioxygenase; InterPro IPR003006: IPR004360; KEGG: bav:BAV0594 2,3-dihydroxybiphenyl 1,2-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Extradiol dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 2,3-dihydroxybiphenyl 1,2-dioxygenase.
       0.773
ADU47355.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR010953: IPR019810; KEGG: nml:Namu_4703 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 
 0.765
ADU49111.1
COGs: COG0372 Citrate synthase; InterPro IPR010953: IPR002020: IPR019810; KEGG: rsa:RSal33209_1176 citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 
 0.765
ADU49644.1
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: nca:Noca_0200 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; TIGRFAM: precorrin 3B synthase CobZ.
 
  
 0.763
ADU47292.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810; KEGG: sma:SAV_3859 citrate synthase 2; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.734
ADU49650.1
Acyl-CoA dehydrogenase type 2 domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mab:MAB_0075 putative hydroxylase; PFAM: Acyl-CoA dehydrogenase type 2 domain; SPTR: Putative hydroxylase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
  
  
 0.711
ADU49642.1
FAD dependent oxidoreductase; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076; KEGG: nca:Noca_0198 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: FAD dependent oxidoreductase; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain.
 
  
 0.677
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.