Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49654.1ABC transporter related protein; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nca:Noca_0100 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter. (514 aa)    
Predicted Functional Partners:
ADU49653.1
Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: nca:Noca_0101 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
 0.999
ADU49655.1
Hypothetical protein; KEGG: nca:Noca_0806 ABC-type sugar transport system periplasmic component-like; SPTR: Putative uncharacterized protein.
  
 0.998
ADU47732.1
Nucleoside ABC transporter membrane protein; COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: nca:Noca_3538 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
   
 0.767
ADU47731.1
Nucleoside ABC transporter membrane protein; COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: nca:Noca_3539 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
     0.762
ADU47729.1
Nucleoside-binding protein; COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: sro:Sros_1269 ABC-type transport system substrate-binding protein; PFAM: basic membrane lipoprotein; SPTR: ABC-type transport system substrate-binding protein; PFAM: Basic membrane protein.
 
   
 0.732
ADU49652.1
Acyl-CoA dehydrogenase type 2 domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mpa:MAP1448c hypothetical protein; PFAM: Acyl-CoA dehydrogenase type 2 domain; SPTR: Pigment production hydroxylase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
       0.578
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.570
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.499
ADU49406.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: kfl:Kfla_1065 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family.
 
  
 0.478
ADU48974.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family.
 
  
 0.465
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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