STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49656.1COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: nca:Noca_0210 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold. (281 aa)    
Predicted Functional Partners:
ADU47614.1
4-oxalocrotonate decarboxylase; COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mjl:Mjls_4208 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 4-oxalocrotonate decarboxylase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
 
 0.970
ADU47617.1
COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: amd:AMED_8623 2-keto-4-pentenoate hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 2-oxopent-4-enoate hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase.
 
 
 0.966
ADU47624.1
Catechol 2,3-dioxygenase; InterPro IPR004360: IPR000486; KEGG: tcu:Tcur_0529 catechol 2,3 dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Catechol 2,3 dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: catechol 2,3 dioxygenase.
  
 
 0.966
ADU47611.1
2-hydroxymuconate semialdehyde hydrolase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: tcu:Tcur_0531 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: 2-hydroxymuconic semialdehyde hydrolase; PFAM: alpha/beta hydrolase fold.
  
  
 
0.918
ADU47612.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: tcu:Tcur_0539 betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Betaine-aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
 
  0.912
ADU49329.1
Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120: IPR020556; KEGG: rop:ROP_37880 putative amidase; PFAM: Amidase; SPTR: Putative amidase; PFAM: Amidase; Belongs to the amidase family.
   
 
 0.902
ADU47616.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
    0.726
ADU47615.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.700
ADU49649.1
Glyoxalase/bleomycin resistance protein/dioxygenase; InterPro IPR003006: IPR004360; KEGG: bav:BAV0594 2,3-dihydroxybiphenyl 1,2-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Extradiol dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 2,3-dihydroxybiphenyl 1,2-dioxygenase.
  
  
 0.663
ADU49650.1
Acyl-CoA dehydrogenase type 2 domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR013107; KEGG: mab:MAB_0075 putative hydroxylase; PFAM: Acyl-CoA dehydrogenase type 2 domain; SPTR: Putative hydroxylase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain.
  
   0.661
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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