STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49657.1Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: cai:Caci_5914 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain. (241 aa)    
Predicted Functional Partners:
ADU49668.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR000759: IPR006076; KEGG: sco:SCO6289 secreted oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Secreted oxidoreductase; PFAM: FAD dependent oxidoreductase.
  
 0.884
ADU49658.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sgr:SGR_1624 putative proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase; Belongs to the proline racemase family.
 
   
 0.874
ADU49661.1
Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sro:Sros_6000 branched-chain amino acid transport system permease protein; PFAM: inner-membrane translocator; SPTR: Branched-chain amino acid transport system permease protein; PFAM: Branched-chain amino acid transport system / permease component.
       0.777
ADU49662.1
Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sro:Sros_6001 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
       0.777
ADU49659.1
Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR017871: IPR003439; KEGG: tbi:Tbis_0408 ABC transporter-like protein; PFAM: ABC transporter related; SPTR: ABC transporter related protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
       0.776
ADU49660.1
Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593; KEGG: sro:Sros_5999 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
       0.773
ADU49666.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR017224: IPR007419; KEGG: sco:SCO6291 secreted oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Putative secreted oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain.
 
     0.737
ADU49664.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sco:SCO6293 hypothetical protein; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: 4-hydroxyproline epimerase; PFAM: Proline racemase.
 
   
 0.696
ADU49665.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: sco:SCO6292 dihydropicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Putative dihydropicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
 
  
 0.688
ADU47642.1
GntR domain protein; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: art:Arth_0271 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.661
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.