Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU49658.1COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sgr:SGR_1624 putative proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase; Belongs to the proline racemase family. (355 aa)    
Predicted Functional Partners:
ADU49664.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sco:SCO6293 hypothetical protein; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: 4-hydroxyproline epimerase; PFAM: Proline racemase.
 
  
 
0.945
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.912
ADU47186.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: ami:Amir_1081 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
    
 0.903
ADU47673.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: amd:AMED_2662 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Putative proline dehydrogenase; PFAM: Proline dehydrogenase.
    
 0.903
ADU47399.1
Proline iminopeptidase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR002410: IPR000073: IPR005944; KEGG: kse:Ksed_01230 proline iminopeptidase; PFAM: alpha/beta hydrolase fold; PRIAM: Prolyl aminopeptidase; SPTR: Proline iminopeptidase; TIGRFAM: proline iminopeptidase; manually curated; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline iminopeptidase, Neisseria-type subfamily; Belongs to the peptidase S33 family.
     
  0.900
ADU49657.1
Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: cai:Caci_5914 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
   
 0.873
ADU49665.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: sco:SCO6292 dihydropicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Putative dihydropicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
 
  
 0.841
ADU49668.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR000759: IPR006076; KEGG: sco:SCO6289 secreted oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Secreted oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
   
 0.797
ADU46676.1
COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: krh:KRH_11610 ornithine cyclodeaminase/mu-crystallin family protein; PFAM: ornithine cyclodeaminase/mu-crystallin; SPTR: Ornithine cyclodeaminase/mu-crystallin family protein; PFAM: Ornithine cyclodeaminase/mu-crystallin family.
 
   
 0.778
ADU49662.1
Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sro:Sros_6001 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
  
    0.776
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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