Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49665.1COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: sco:SCO6292 dihydropicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Putative dihydropicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (299 aa)    
Predicted Functional Partners:
ADU49666.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR017224: IPR007419; KEGG: sco:SCO6291 secreted oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Putative secreted oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain.
 
  
 0.990
ADU49668.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR000759: IPR006076; KEGG: sco:SCO6289 secreted oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Secreted oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
  
 0.990
ADU49669.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ach:Achl_0350 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
 
 0.960
ADU49664.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sco:SCO6293 hypothetical protein; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: 4-hydroxyproline epimerase; PFAM: Proline racemase.
 
  
 0.949
ADU49667.1
KEGG: cai:Caci_5918 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.892
ADU49658.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sgr:SGR_1624 putative proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase; Belongs to the proline racemase family.
 
  
 0.841
ADU49657.1
Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: cai:Caci_5914 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.694
ADU48814.1
COGs: COG1605 Chorismate mutase; InterPro IPR010951: IPR002701: IPR020822; KEGG: sgr:SGR_5509 chorismate mutase; PFAM: Chorismate mutase, type II; SPTR: Chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, alpha proteobacterial type.
  
  
 0.605
gatC
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
  
 0.600
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.579
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.