Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49693.1COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR000169: IPR006092: IPR006091: IPR006090; KEGG: tbi:Tbis_2866 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (401 aa)    
Predicted Functional Partners:
ADU49694.1
COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR008266: IPR002575; KEGG: nfa:nfa34090 putative phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: Putative phosphotransferase; PFAM: Phosphotransferase enzyme family.
   0.995
ADU49695.1
COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: svi:Svir_16780 acyl dehydratase; PFAM: MaoC domain protein dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: Acyl dehydratase; PFAM: MaoC like domain.
 
 0.954
ADU48424.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155: IPR020613; KEGG: cai:Caci_6777 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.946
ADU48902.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: nca:Noca_1813 short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.946
ADU46815.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: gob:Gobs_3773 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.945
ADU46807.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089: IPR004167: IPR001078; KEGG: kse:Ksed_02370 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: Putative dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid [...]
   
  0.916
ADU50004.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: nca:Noca_4292 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
  
  
 
0.907
ADU48425.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.886
ADU49697.1
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR020904: IPR002347: IPR002198; KEGG: nca:Noca_1829 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
 
     0.831
ADU49696.1
3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: nfa:nfa23600 putative short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative short chain dehydrogenase; PFAM: short chain dehydrogenase.
  
  0.824
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (10%) [HD]